Center for Applied Proteomics and Molecular Medicine

Publications

257 entries « 4 of 6 »

2014

L, Colarossi; L, Memeo; C, Colarossi; E, Aiello; A, Iuppa; V, Espina; L, Liotta; C, Mueller

Inhibition of histone deacetylase 4 increases cytotoxicity of docetaxel in gastric cancer cells Journal Article

In: Proteomics Clin Appl, vol. 8, iss. 11-12, pp. 924-31, 2014.

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TG, Popova; V, Espina; W, Zhou; C, Mueller; L, Liotta; SG, Popov

Whole proteome analysis of mouse lymph nodes in cutaneous anthrax Journal Article

In: PLoS One, vol. 9, iss. 10, no. e110873, 2014.

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YE, Castro-Sesquen; RH, Gilman; G, Galdos-Cardenas; L, Ferrufino; G, Sánchez; E, Valencia Ayala; L, Liotta; C, Bern; A, Luchini; on Chagas Disease in Bolivia, Working Group; Peru,

Use of a novel chagas urine nanoparticle test (chunap) for diagnosis of congenital chagas disease Journal Article

In: PLoS Negl Trop Dis, vol. 8, iss. 10, no. e3211, 2014.

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GS, Jameson; EF, Petricoin; J, Sachdev; LA, Liotta; DM, Loesch; SP, Anthony; MK, Chadha; JD, Wulfkuhle; RI, Gallagher; KA, Reeder; M, Pierobon; MR, Fulk; NA, Cantafio; B, Dunetz; WD, Mikrut; DD, Von Hoff; NJ, Robert

A pilot study utilizing multi-omic molecular profiling to find potential targets and select individualized treatments for patients with previously treated metastatic breast cancer Journal Article

In: Breast Cancer Res Treat, vol. 147, iss. 3, pp. 579-88, 2014.

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R, Magni; BH, Espina; LA, Liotta; A, Luchini; V, Espina

Hydrogel nanoparticle harvesting of plasma or urine for detecting low abundance proteins Journal Article

In: J Vis Exp, iss. 90, no. e51789, 2014.

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A, Luchini; V, Espina; LA, Liotta

Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces Journal Article

In: Nat Commun, vol. 5, no. 4413, 2014.

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M, Pierobon; A, Silvestri; A, Spira; A, Reeder; E, Pin; S, Banks; E, Parasido; K, Edmiston; L, Liotta; 3rd, Petricoin E

Pilot phase I/II personalized therapy trial for metastatic colorectal cancer: evaluating the feasibility of protein pathway activation mapping for stratifying patients to therapy with imatinib and panitumumab Journal Article

In: J Proteome Res, vol. 13, iss. 6, pp. 2846-55, 2014.

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E, Jaworski; M, Saifuddin; G, Sampey; N, Shafagati; R, Van Duyne; S, Iordanskiy; K, Kehn-Hall; L, Liotta; 3rd, Petricoin E; M, Young; B, Lepene; F, Kashanchi

The use of Nanotrap particles technology in capturing HIV-1 virions and viral proteins from infected cells Journal Article

In: PLoS One, vol. 9, iss. 5, no. e96778, 2014.

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R, Akbani; KF, Becker; N, Carragher; T, Goldstein; de Koning L,; U, Korf; L, Liotta; GB, Mills; SS, Nishizuka; M, Pawlak; 3rd, Petricoin EF; HB, Pollard; B, Serrels; J, Zhu

Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society Journal Article

In: Mol Cell Proteomics, vol. 13, iss. 7, pp. 1625-43, 2014.

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LA, Liotta; 3rd, Petricoin EF

Multiplex proteomic analysis of cells in fine needle aspiration samples: how soon can we expect to individualize therapy by comparing pre- and posttreatment biopsies? Journal Article

In: Clin Chem, vol. 60, iss. 9, pp. 1143-5, 2014.

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J, Bertacchini; M, Guida; B, Accordi; L, Mediani; AM, Martelli; P, Barozzi; 3rd, Petricoin E; L, Liotta; G, Milani; M, Giordan; M, Luppi; F, Forghieri; A, De Pol; L, Cocco; G, Basso; S, Marmiroli

Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis Journal Article

In: Leukemia, vol. 28, iss. 11, pp. 2197-205, 2014.

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N, Shafagati; A, Patanarut; A, Luchini; L, Lundberg; C, Bailey; 3rd, Petricoin E; L, Liotta; A, Narayanan; B, Lepene; K, Kehn-Hall

The use of Nanotrap particles for biodefense and emerging infectious disease diagnostics Journal Article

In: Pathog Dis, vol. 71, iss. 2, pp. 164-76, 2014.

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M, Cremona; V, Espina; D, Caccia; S, Veneroni; M, Colecchia; M, Pierobon; J, Deng; C, Mueller; G, Procopio; C, Lanzi; MG, Daidone; WC, Cho; 3rd, Petricoin EF; L, Liotta; I, Bongarzone

Stratification of clear cell renal cell carcinoma by signaling pathway analysis Journal Article

In: Expert Rev Proteomics, vol. 11, iss. 2, pp. 237-49, 2014.

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M, Amaya; K, Voss; G, Sampey; S, Senina; de la Fuente C,; C, Mueller; V, Calvert; K, Kehn-Hall; C, Carpenter; F, Kashanchi; C, Bailey; S, Mogelsvang; 3rd, Petricoin E; A, Narayanan

The role of IKKβ in Venezuelan equine encephalitis virus infection Journal Article

In: PLoS One, vol. 9, iss. 2, no. e86745, 2014.

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C, Mueller; deCarvalho AC,; T, Mikkelsen; NL, Lehman; V, Calvert; V, Espina; LA, Liotta; 3rd, Petricoin EF

Glioblastoma cell enrichment is critical for analysis of phosphorylated drug targets and proteomic-genomic correlations Journal Article

In: Cancer Res, vol. 74, iss. 3, pp. 818-28, 2014.

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B, Salhia; J, Kiefer; JT, Ross; R, Metapally; RA, Martinez; KN, Johnson; DM, DiPerna; KM, Paquette; S, Jung; S, Nasser; G, Wallstrom; W, Tembe; A, Baker; J, Carpten; J, Resau; T, Ryken; Z, Sibenaller; EF, Petricoin; LA, Liotta; RK, Ramanathan; ME, Berens; NL, Tran

Integrated genomic and epigenomic analysis of breast cancer brain metastasis Journal Article

In: PLoS One, vol. 9, iss. 1, no. e85448, 2014.

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A, Narayanan; M, Amaya; K, Voss; M, Chung; A, Benedict; G, Sampey; K, Kehn-Hall; A, Luchini; L, Liotta; C, Bailey; A, Kumar; S, Bavari; RM, Hakami; F, Kashanchi

Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells Journal Article

In: Virology, vol. 449, pp. 270-86, 2014.

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A, Conti; V, Espina; A, Chiechi; G, Magagnoli; C, Novello; L, Pazzaglia; I, Quattrini; P, Picci; LA, Liotta; MS, Benassi

Mapping protein signal pathway interaction in sarcoma bone metastasis: linkage between rank, metalloproteinases turnover and growth factor signaling pathways Journal Article

In: Clin Exp Metastasis, vol. 31, iss. 1, pp. 15-24, 2014.

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2013

L, Xu; AG, Elkahloun; F, Candotti; A, Grajkowski; SL, Beaucage; EF, Petricoin; V, Calvert; H, Juhl; F, Mills; K, Mason; N, Shastri; J, Chik; C, Xu; AS, Rosenberg

A novel function of RNAs arising from the long terminal repeat of human endogenous retrovirus 9 in cell cycle arrest Journal Article

In: J Virol, vol. 87, iss. 1, pp. 25-36, 2013.

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B, Chirullo; R, Sgarbanti; D, Limongi; IL, Shytaj; D, Alvarez; B, Das; A, Boe; S, DaFonseca; N, Chomont; L, Liotta; EI, Petricoin; S, Norelli; E, Pelosi; E, Garaci; A, Savarino; AT, Palamara

A candidate anti-HIV reservoir compound, auranofin, exerts a selective 'anti-memory' effect by exploiting the baseline oxidative status of lymphocytes Journal Article

In: Cell Death Dis, vol. 4, iss. 12, no. e944, 2013.

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FA, Holmes; V, Espina; LA, Liotta; YM, Nagarwala; M, Danso; KJ, McIntyre; CR, Osborne; T, Anderson; L, Krekow; JL, Blum; J, Pippen; A, Florance; J, Mahoney; JA, O'Shaughnessy

Pathologic complete response after preoperative anti-HER2 therapy correlates with alterations in PTEN, FOXO, phosphorylated Stat5, and autophagy protein signaling Journal Article

In: BMC Res Notes, vol. 6, no. 508, 2013.

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W, Zhou; LA, Liotta; EF, Petricoin

Cancer metabolism and mass spectrometry-based proteomics Journal Article

In: Cancer Lett, vol. 356, iss. 2 Pt A, pp. 176-183, 2013.

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J, Bosch; A, Luchini; S, Pichini; D, Tamburro; C, Fredolini; L, Liotta; E, Petricoin; R, Pacifici; F, Facchiano; J, Segura; E, Garaci; R, Gutiérrez-Gallego

Analysis of urinary human growth hormone (hGH) using hydrogel nanoparticles and isoform differential immunoassays after short recombinant hGH treatment: preliminary results Journal Article

In: J Pharm Biomed Anal, vol. 85, pp. 194-197, 2013.

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W, Xia; 3rd, Petricoin EF; S, Zhao; L, Liu; T, Osada; Q, Cheng; JD, Wulfkuhle; WR, Gwin; X, Yang; RI, Gallagher; S, Bacus; HK, Lyerly; NL, Spector

An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models Journal Article

In: Breast Cancer Res, vol. 15, iss. 5, no. R85, 2013.

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B, Wilson; LA, Liotta; 3rd, Petricoin E

Dynamic protein pathway activation mapping of adipose-derived stem cell differentiation implicates novel regulators of adipocyte differentiation Journal Article

In: Mol Cell Proteomics, vol. 12, iss. 9, pp. 2522-35, 2013.

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T, Hricik; G, Federici; A, Zeuner; G, Alimena; A, Tafuri; V, Tirelli; L, Varricchio; F, Masiello; F, Ciaffoni; S, Vaglio; 3rd, Petricoin EF; G, Girelli; RL, Levine; AR, Migliaccio

Transcriptomic and phospho-proteomic analyzes of erythroblasts expanded in vitro from normal donors and from patients with polycythemia vera Journal Article

In: Am J Hematol, vol. 88, iss. 9, pp. 723-729, 2013.

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L, Biasutto; A, Chiechi; R, Couch; LA, Liotta; V, Espina

Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress Journal Article

In: Exp Cell Res, vol. 319, iss. 13, pp. 2113-2123, 2013.

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G, Federici; X, Gao; J, Slawek; T, Arodz; A, Shitaye; JD, Wulfkuhle; R, De Maria; LA, Liotta; 3rd, Petricoin EF

Systems analysis of the NCI-60 cancer cell lines by alignment of protein pathway activation modules with "-OMIC" data fields and therapeutic response signatures Journal Article

In: Mol Cancer Res, vol. 11, iss. 6, pp. 676-85, 2013.

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Y, Zhan; B, Cao; Y, Qi; S, Liu; Q, Zhang; W, Zhou; D, Xu; H, Lu; O, Sartor; W, Kong; H, Zhang; Y, Dong

Methylselenol prodrug enhances MDV3100 efficacy for treatment of castration-resistant prostate cancer Journal Article

In: Int J Cancer, vol. 133, iss. 9, pp. 2225-2233, 2013.

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A, Chiechi; C, Novello; G, Magagnoli; 3rd, Petricoin EF; J, Deng; MS, Benassi; P, Picci; I, Vaisman; V, Espina; LA, Liotta

Elevated TNFR1 and serotonin in bone metastasis are correlated with poor survival following bone metastasis diagnosis for both carcinoma and sarcoma primary tumors Journal Article

In: Clin Cancer Res, vol. 19, iss. 9, pp. 2473-85, 2013.

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E, Pin; C, Fredolini; 3rd, Petricoin EF

The role of proteomics in prostate cancer research: biomarker discovery and validation Journal Article

In: Clin Biochem, vol. 46, iss. 6, pp. 524-538, 2013.

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W, Zhou; M, Capello; C, Fredolini; L, Racanicchi; E, Dugnani; L, Piemonti; LA, Liotta; F, Novelli; 3rd, Petricoin EF

Mass spectrometric analysis reveals O-methylation of pyruvate kinase from pancreatic cancer cells Journal Article

In: Anal Bioanal Chem, vol. 405, iss. 14, pp. 4937-43, 2013.

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Y, Zhang; KE, Farenholtz; Y, Yang; F, Guessous; CG, Dipierro; VS, Calvert; J, Deng; D, Schiff; W, Xin; JK, Lee; B, Purow; J, Christensen; E, Petricoin; R, Abounader

Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition Journal Article

In: Clin Cancer Res, vol. 19, iss. 6, pp. 1433-44, 2013.

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A, Silvestri; V, Calvert; C, Belluco; M, Lipsky; R, De Maria; J, Deng; A, Colombatti; F, De Marchi; D, Nitti; E, Mammano; L, Liotta; E, Petricoin; M, Pierobon

Protein pathway activation mapping of colorectal metastatic progression reveals metastasis-specific network alterations Journal Article

In: Clin Exp Metastasis, vol. 30, iss. 3, pp. 309-316, 2013.

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V, Espina; J, Wysolmerski; K, Edmiston; LA, Liotta

Attacking breast cancer at the preinvasion stage by targeting autophagy Journal Article

In: Womens Health (Lond), vol. 9, iss. 2, pp. 157-170, 2013.

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S, Page; A, Birerdinc; M, Estep; M, Stepanova; A, Afendy; 3rd, Petricoin E; ZM, Younossi; V, Chandhoke; A, Baranova

Knowledge-Based Identification of Soluble Biomarkers: Hepatic Fibrosis in NAFLD as an Example Journal Article

In: PLoS One, vol. 8, iss. 2, no. e56009, 2013.

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C, Albanese; OC, Rodriguez; J, VanMeter; ST, Fricke; BR, Rood; Y, Lee; SS, Wang; S, Madhavan; Y, Gusev; 3rd, Petricoin EF; Y, Wang

Preclinical magnetic resonance imaging and systems biology in cancer research: current applications and challenges Journal Article

In: Am J Pathol, vol. 182, iss. 2, pp. 312-318, 2013.

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MI, Sereni; M, Pierobon; R, Angioli; 3rd, Petricoin EF; MJ, Frederick

Reverse phase protein microarrays and their utility in drug development Book Chapter

In: vol. 986, pp. 187-214, Humana Press, Totowa, NJ, Target Identification and Validation in Drug Discovery, 2013, ISBN: 978-1-62703-310-7.

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M, Pierobon; CL, Frankenfeld

Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis Journal Article

In: Breast Cancer Res Treat, vol. 137, iss. 1, pp. 307-14, 2013.

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2012

E, Pin; C, Fredolini; 3rd, Petricoin EF

The role of proteomics in prostate cancer research: biomarker discovery and validation Journal Article

In: Clin Biochem, vol. 46, iss. 6, pp. 524-38, 2012.

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A, Zupa; G, Improta; A, Silvestri; E, Pin; J, Deng; M, Aieta; P, Musto; D, Nitti; E, Mammano; L, Liotta; C, Belluco; J, Wulfkuhle; 3rd, Petricoin E

A pilot characterization of human lung NSCLC by protein pathway activation mapping Journal Article

In: J Thorac Oncol, vol. 7, iss. 12, pp. 1755-1766, 2012.

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JD, Wulfkuhle; D, Berg; C, Wolff; R, Langer; K, Tran; J, Illi; V, Espina; M, Pierobon; J, Deng; A, DeMichele; A, Walch; H, Bronger; I, Becker; C, Waldhör; H, Höfler; L, Esserman; Investigators, I-SPY 1 TRIAL; LA, Liotta; KF, Becker; 3rd, Petricoin EF

Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping Journal Article

In: Clin Cancer Res, vol. 18, iss. 23, pp. 6426-35, 2012.

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Q, Jin; NR, Pulipati; W, Zhou; CM, Staub; LA, Liotta; KM, Mulder

Role of km23-1 in RhoA/actin-based cell migration Journal Article

In: Biochem Biophys Res Commun, vol. 428, iss. 3, pp. 333-8, 2012.

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B, Accordi; L, Galla; G, Milani; M, Curtarello; V, Serafin; V, Lissandron; G, Viola; te Kronnie G,; R, De Maria; 3rd, Petricoin E; LA, Liotta; S, Indraccolo; G, Basso

AMPK inhibition enhances apoptosis in MLL-rearranged pediatric B-acute lymphoblastic leukemia cells Journal Article

In: Leukemia, vol. 27, pp. pages1019–1027, 2012.

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van Agthoven T,; MF, Godinho; JD, Wulfkuhle; 3rd, Petricoin EF; LC, Dorssers

Protein pathway activation mapping reveals molecular networks associated with antiestrogen resistance in breast cancer cell lines Journal Article

In: Int J Cancer, vol. 131, iss. 9, pp. 1998-2007, 2012.

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W, Zhou; LA, Liotta; 3rd, Petricoin EF

Cancer metabolism: what we can learn from proteomic analysis by mass spectrometry Journal Article

In: Cancer Genomics Proteomics, vol. 9, iss. 6, pp. 373-81, 2012.

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A, Luchini; D, Tamburro; R, Magni; C, Fredolini; V, Espina; J, Bosch; E, Garaci; 3rd, Petricoin EF; LA, Liotta

Application of Analyte Harvesting Nanoparticle Technology to the Measurement of Urinary HGH in Healthy Individuals Journal Article

In: J Sports Med Doping Stud, vol. 2, iss. 6, no. e127, 2012.

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D, Kanojia; W, Zhou; J, Zhang; C, Jie; PK, Lo; Q, Wang; H, Chen

Proteomic profiling of cancer stem cells derived from primary tumors of HER2/Neu transgenic mice Journal Article

In: Proteomics, vol. 12, iss. 22, pp. 3407-15, 2012.

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MF, Godinho; JD, Wulfkuhle; MP, Look; AM, Sieuwerts; S, Sleijfer; JA, Foekens; 3rd, Petricoin EF; LC, Dorssers; van Agthoven T,

BCAR4 induces antioestrogen resistance but sensitises breast cancer to lapatinib Journal Article

In: Br J Cancer, vol. 107, iss. 6, pp. 947-55, 2012.

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SA, Hartsink-Segers; CM, Zwaan; C, Exalto; MW, Luijendijk; VS, Calvert; EF, Petricoin; WE, Evans; D, Reinhardt; de Haas V,; M, Hedtjärn; BR, Hansen; T, Koch; HN, Caron; R, Pieters; ML, Den Boer

Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target Journal Article

In: Leukemia, vol. 27, iss. 3, pp. 560-8, 2012.

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257 entries « 4 of 6 »